Layer-Specific Refinement of Sensory Coding in Developing Mouse Barrel Cortex
نویسندگان
چکیده
منابع مشابه
Facilitating sensory responses in developing mouse somatosensory barrel cortex.
The sensory responses in the barrel cortex of mice aged postnatal day (P)7-P12 evoked by a single whisker deflection are smaller in amplitude and spread over a smaller area than those measured in P13-P21 mice. However, repetitive 10-Hz stimulation or paired pulse whisker stimulation in P7-P12 mice evoked facilitating sensory responses, contrasting with the depressing sensory responses observed ...
متن کاملMorphological heterogeneity of layer VI neurons in mouse barrel cortex.
Understanding the basic neuronal building blocks of the neocortex is a necessary first step toward comprehending the composition of cortical circuits. Neocortical layer VI is the most morphologically diverse layer and plays a pivotal role in gating information to the cortex via its feedback connection to the thalamus and other ipsilateral and callosal corticocortical connections. The heterogene...
متن کاملLayer- and Column-Specific Knockout of NMDA Receptors in Pyramidal Neurons of the Mouse Barrel Cortex
Viral vectors injected into the mouse brain offer the possibility for localized genetic modifications in a highly controlled manner. Lentivector injection into mouse neocortex transduces cells within a diameter of approximately 200mum, which closely matches the lateral scale of a column in barrel cortex. The depth and volume of the injection determines which cortical layer is transduced. Furthe...
متن کاملLayer, Column and Cell-Type Specific Genetic Manipulation in Mouse Barrel Cortex
Sensory information is processed in distributed neuronal networks connected by intricate synaptic circuits. Studies of the rodent brain can provide insight into synaptic mechanisms of sensory perception and associative learning. In particular, the mouse whisker sensorimotor system has recently begun to be investigated through combinations of imaging and electrophysiology, providing data correla...
متن کاملPostnatal Changes of Conduction Velocity of the Fibers in and out of the Mouse Barrel Cortex
There are some conflicts about constancy of conduction velocity (CV) in a given tract of nervous system. By recording excitatory postsynaptic currents (EPSC) in layer IV of the somatosensory cortex we tried to clear changes in CV of thalamocortical tract of mice aged 3 to 50 days old. Field potentials and EPSC were recorded in the layer IV by stimulation of ventrobasal nucleus of thalamus (VB) ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cerebral Cortex
سال: 2016
ISSN: 1047-3211,1460-2199
DOI: 10.1093/cercor/bhw280